Santa Cruz Vacations from $1,135
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Your Santa Cruz Vacation
Booking a Santa Cruz vacation package is a good way to become acquainted with this unique neighborhood. From its must-visit places to its lesser-known treasures, there's a lot to delve into. Some leading nearby attractions to check out during your trip to Santa Cruz include Seville Cathedral, Alcázar and Plaza de España. Whatever your dream Santa Cruz vacation looks like, you can turn it into reality with Expedia.
The Latest Santa Cruz Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Apartamentos Metrópolis Sevilla
Historical Center
$1,135
per person
Nov 4 - Nov 9
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
8.8/10 Excellent! (188 reviews)
The apartment is clean, organized and has everything you need. It is close to city center where you find bars and restaurants. Front desk is so nice and helpful.. Excellent place to stay in Sevilla .
Reviewed on May 2, 2026
Aguilas5 SevillaSuites
Historical Center
$1,364
per person
Nov 4 - Nov 9
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
10/10 Exceptional! (530 reviews)
The accommodations were clean, the check in was smooth, and our specific room had a kitchenette with utensils and large fridge. German (Herman) and Jose were outstanding. They are quick to answer questions via WhatsApp or in the lobby. The best part of our stay is the location! A 10 minute walk to Alcazar and the Cathedral, and the “waffle” looking structure. Lots of restaurants downstairs. And Carrefour a few steps away. The suites5 was perfect for our stay in Seville!
Reviewed on Aug 9, 2026
Eurostars Sevilla Boutique
Historical Center
$1,390
per person
Nov 4 - Nov 9
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
9/10 Wonderful! (530 reviews)
Wonderful hotel, beautiful rooms, friendly staff, and the added bonus of an outdoor swimming pool. We had a fabulous overnight stay.
Reviewed on Aug 16, 2026
Hotel Kivir Adults Recommended, Historic City Center
Historical Center
$1,445
per person
Nov 4 - Nov 9
found 1 day ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
9.8/10 Exceptional! (603 reviews)
This hotel has got to be up there with one of the nicest hotels I’ve ever stayed at.
From the moment we entered the doors, it felt like luxury. The staff were extremely friendly and helpful, the room was spotless and to a high standard.
The little touches such as the free coffee/snack corner and the free bar from 4pm-7:30pm just added to the enjoyment of our staff.
I would highly recommend and would love to visit again
Reviewed on Aug 16, 2026
Where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Historical Center
7 out of top 10 points of interest in this area
Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.
El Arenal
Located in Seville's historical center, El Arenal boasts the 13th-century Torre del Oro, Royal Shipyards, and La Real Maestranza bullring. Explore this vibrant area on the Guadalquivir river's east bank.
Alfalfa
Sightsee and feast on local specialties in a part of Seville’s old town district that’s filled with lots of places to eat and socialize.
Triana
1 out of top 10 points of interest in this area
Discover traditional pottery and vibrant flamenco culture in this lively area. Shop at Triana Market for local crafts and tapas, or explore Calle Betis for popular restaurants, bars, and nightclubs.
San Bartolomé
Travelers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.
Santa Cruz Hotel Deals
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
San Fernando 2 Seville Seville
$516 nightly
$567 total
Sep 1 - Sep 2
Total with taxes and fees
Las Casas de la Judería, Sevilla Historic City Center
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
$141 nightly
$155 total
Aug 31 - Sep 1
Total with taxes and fees
9.2/10 Wonderful! (1,001 reviews)
"Lovely hotel, with nice and helpful staff."
Reviewed on Aug 30, 2026
Hotel Fernando III
San Jose 21 Seville Seville
Fully refundableReserve now, pay when you stay
$136 nightly
$149 total
Aug 31 - Sep 1
Total with taxes and fees
9.6/10 Exceptional! (1,447 reviews)
"I was in a superior room which was spacious and modern in character. Nice wet room and large bed. Maid service every day. Staff were helpful."
Reviewed on Aug 21, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Santa Cruz attractions
Royal Alcázar of Seville
9.6/10 (8,220 reviews)
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
Giralda Tower
9.4/10 (6,353 reviews)
Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.
San Telmo Palace
Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.
University of Seville
8.6/10 (1,316 reviews)
Enjoy the collegiate vibe when you visit University of Seville, during your travels in Paseo de Las Delicias. Visit the shops and stunning cathedral in this culturally rich area.
Santa Cruz Church
8.6/10 (26 reviews)
After visiting Santa Cruz Church, make a plan to see the other sights and activities in Seville. Check out the shops and top-notch restaurants in this romantic area.
Murillo Gardens
9.2/10 (9 reviews)
Explore the great outdoors at Murillo Gardens, a lovely green space in Seville. Visit the shops and stunning cathedral in this family-friendly area.
General Archive of the Indies
8.0/10 (11 reviews)
You can study the exhibits at General Archive of the Indies, a museum with a story of its own, during your travels to Seville. Check out the shops and lively bars in this culturally rich area.
Santa María la Blanca Church
8.4/10 (8 reviews)
After visiting Santa María la Blanca Church, make a plan to see the other sights and activities in Seville. Check out the stunning cathedral and top-notch restaurants in this culturally rich area.
Things to do
Cathedral & Alcázar of Seville Guided Tour Combo
$35
per adult
88% of travellers recommend
Seville Guided Tour with Fast-Track Entry to Alcázar, Cathedral & Giralda
$89
per adult
88% of travellers recommend
Granada Day Trip from Seville with Alhambra Guided Tour Included
$197
per adult
86% of travellers recommend
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- Flights from Madrid (MAD) to Seville (SVQ)
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- Flights to Andalusia
- Cabildo Plaza
- Visit Santa Cruz
- Seville Vacations
- Metropol Parasol
- Visit La Cartuja Island
- Casa del Flamenco Theater
- Andalusia Vacations
- El Postigo Market
- Visit Los Remedios
- Royal Alcázar of Seville
- Basilica of the Macarena
- Paseo de Cristóbal Colón
- Santa María la Blanca Church
- San Telmo Palace
- Province of Seville Vacations
- Maria Luisa Park
- Giralda Tower
- Triunfo Plaza
- General Archive of the Indies
- Archbishop's Palace
- Casa de la Memoria Cultural Center
- Visit Historical Center
- Plaza Nueva
- Visit El Arenal
- Plaza de San Francisco
- All inclusive Vacation Packages Seville
- Calle Sierpes
- Juderia de Sevilla Interpretation Center
- Visit Andalusia
- Salvador Plaza
- Torre del Oro Watchtower
- Visit Seville
- Triana Bridge
- Museum of Fine Arts
- Seville Cathedral
- Seville Town Hall
- Convent of the Incarnation
- Visit Triana
- Plaza de la Encarnación
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.