Santa Cruz Vacations from $957
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Your Santa Cruz Vacation
Booking a Santa Cruz vacation package is a good way to become acquainted with this unique neighborhood. From its must-visit places to its lesser-known treasures, there's a lot to delve into. Some leading nearby attractions to check out during your trip to Santa Cruz include Seville Cathedral, Alcázar and Plaza de España. Whatever your dream Santa Cruz vacation looks like, you can turn it into reality with Expedia.
The Latest Santa Cruz Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Apartamentos Metrópolis Sevilla
Historical Center
Price was $1,370, price is now $957 per person
$957
per person
Feb 12 - Feb 18
found 12 hours ago
Roundtrip flight included
Dallas (DFW) to Seville (SVQ)
8.8/10 Excellent! (176 reviews)
The location of this apartment is perfect - close to all touristic locations and pretty decent dining options etc.
Reviewed on Dec 23, 2025
Eurostars Sevilla Boutique
Historical Center
Price was $2,049, price is now $1,449 per person
$1,449
per person
Mar 21 - Mar 27
found 10 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
9/10 Wonderful! (481 reviews)
Room was spotless, staff was courteous and location was perfect!
Reviewed on Nov 17, 2025
Hotel Boutique Corral del Rey by ALUZ Collection
Historical Center
Price was $2,147, price is now $1,547 per person
$1,547
per person
Mar 21 - Mar 27
found 10 hours ago
Roundtrip non-stop flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
9.6/10 Exceptional! (89 reviews)
Staff was extremely helpful and always very pleasant.
Reviewed on Dec 11, 2025
Where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Historical Center
8 out of top 10 points of interest in this area
4.5/5(600 area reviews)
Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.
Santa Cruz Hotel Deals
Las Casas de la Judería, Sevilla Historic City Center
Calle Santa Maria La Blanca 5 Seville Seville
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $120 total per night from Jan 19 to Jan 20
$120 total
Jan 19 - Jan 20
Total with taxes and fees
9.2/10 Wonderful! (1,008 reviews)
The hotel is very unique and interesting, feels like it’s a museum. The staff member is fine, the room is clean but a little old.
Reviewed on Jan 4, 2026
Hotel Amadeus Sevilla
Calle Farnesio 6 Seville Seville
Fully refundableReserve now, pay when you stay
$123 nightly
The price is $135 total per night from Jan 9 to Jan 10
$135 total
Jan 9 - Jan 10
Total with taxes and fees
9.6/10 Exceptional! (1,115 reviews)
Very nice room, excellent staff and nice position
Reviewed on Jan 5, 2026
Hotel Fernando III
San Jose 21 Seville Seville
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $124 total per night from Jan 11 to Jan 12
$124 total
Jan 11 - Jan 12
Total with taxes and fees
9.6/10 Exceptional! (1,532 reviews)
We stayed at this hotel over Christmas. We found it well located to explore the city centre and the staff were friendly and helpful.The breakfasts were excellent and even included Bucks Fizz!
Reviewed on Jan 5, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Cruz
Royal Alcázar of Seville
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
Giralda Tower
Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.
San Telmo Palace
Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.
Things to do
Cathedral & Alcázar of Seville Guided Tour Combo
$39
per adult
92% of travellers recommend
Sevilla Food Tour: Tapas, Wine, History & Traditions
$88
per adult
100% of travellers recommend
Flamenco Show at Tablao El Arenal with Drink and Optional Dinner or Tapas
$55
per adult
96% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.