Santa Cruz Vacations from $975
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Your Santa Cruz Vacation
Booking a Santa Cruz vacation package is a good way to become acquainted with this unique neighborhood. From its must-visit places to its lesser-known treasures, there's a lot to delve into. Some leading nearby attractions to check out during your trip to Santa Cruz include Seville Cathedral, Alcázar and Plaza de España. Whatever your dream Santa Cruz vacation looks like, you can turn it into reality with Expedia.
The Latest Santa Cruz Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Cavalta Boutique Hotel – Small Luxury Hotel
Triana
Price was $1,407, price is now $975 per person
$975
per person
Nov 5 - Nov 9
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
9.8/10 Exceptional! (41 reviews)
Lovely quaint quiet hotel walking distance to main centre.
Reviewed on Sep 19, 2025
Aguilas5 SevillaSuites
Historical Center
Price was $1,639, price is now $1,054 per person
$1,054
per person
Nov 5 - Nov 9
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
10/10 Exceptional! (516 reviews)
The stay here was very nice from start to finish. Communication was prompt, check-in and out was easy. German and Jose were excellent hosts. Was concerned at first being on the ground floor facing the street thinking it would be noisy but it was very quiet and slept well. The space was comfortable, very clean, nicely decorated. Many restaurants, bars, attractions were all close by within walking distance. Bakery on the corner and a supermarket right around the corner. Excellent WiFi and a/c. Definitely enjoyed my stay here and wouldn’t hesitate to stay here again. My only minor suggestions would be to have a large complimentary water bottle upon arrival and a roll of paper towels for the kitchen.
Thank you German and Jose for a great stay!
Reviewed on Oct 2, 2025
Hotel Boutique Corral del Rey by ALUZ Collection
Historical Center
Save 100% on your flight
Price was $2,210, price is now $1,508 per person
$1,508
per person
Nov 5 - Nov 9
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
9.6/10 Exceptional! (83 reviews)
What to say: the room I had was beautiful and the twin shower was larger than some hotel rooms ive stayed in! Understated, focus on quality, and nice touches such as a hand written note from the owner.
Breakfast was fresh and delicious.
My only negative was i was only there overnight! Would be a wonderful base for a long weekend in Seville.
Reviewed on Aug 31, 2025
Hotel Las Casas de El Arenal by Casas y Palacios
Historical Center
Price was $1,383, price is now $1,076 per person
$1,076
per person
Nov 5 - Nov 9
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
9.4/10 Exceptional! (955 reviews)
Wonderful hotel. Beautiful
Grounds. Perfect location in the historic Jewish Quarters. Staff were amazing.
Reviewed on Oct 3, 2025
Hotel Colón Gran Meliá
Historical Center
Price was $1,679, price is now $1,324 per person
$1,324
per person
Nov 5 - Nov 9
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Seville (SVQ)
9.4/10 Exceptional! (1,003 reviews)
Property was excellent!! But I feel that my bill was overcharged!! They upgraded me at my request but did not take into account the credit for my pre- paid reservation!!
Reviewed on Sep 10, 2025
Where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Historical Center
7 out of top 10 points of interest in this area
4.5/5(600 area reviews)
Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.
Santa Cruz Hotel Deals
Las Casas de la Juderia
Calle Santa Maria La Blanca 5, Seville, Seville
Fully refundableReserve now, pay when you stay
$170 nightly
The price is $187 total per night from Nov 2 to Nov 3
$187 total
Nov 2 - Nov 3
Total with taxes and fees
9.2/10 Wonderful! (1,024 reviews)
"Amazing hotel complex. Beautiful rooms. In the centre of old Sevilla."
Reviewed on Sep 25, 2025
Hotel Rey Alfonso X
Calle Ximenez De Enciso, 35, Seville, Seville
$179 nightly
The price is $197 total per night from Nov 3 to Nov 4
$197 total
Nov 3 - Nov 4
Total with taxes and fees
9.4/10 Exceptional! (1,074 reviews)
"Great location of the hotel - all main attractions within walking distance. The hotel itself is lovely with friendly polite staff. A couple of issues: sound isolation is not great with marble and metal floors - you litelly can hear everyone in the corridor and the room upstairs, also the air- conditioner ..."
Reviewed on Sep 29, 2025
Hotel Murillo
Calle Lope de Rueda, 7-9, Seville, Seville
Fully refundable
$103 nightly
The price is $113 total per night from Oct 30 to Oct 31
$113 total
Oct 30 - Oct 31
Total with taxes and fees
8.6/10 Excellent! (1,000 reviews)
Excellent location, great staff, basic bedroom
"The lobby/reception area is beautiful, and I was checked in by a wonderfully friendly member of staff. My room is what can best be described as dated. It was clean but things like the bed not having a headboard or the curtains not being made from blackout material brings down the overall feel of ..."
Reviewed on Sep 30, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Cruz
Royal Alcázar of Seville
5/5(735 reviews)
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
Giralda Tower
4.5/5(496 reviews)
Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.
San Telmo Palace
Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.
Things to do
Cathedral & Alcázar of Seville Guided Tour Combo
$39
per adult
92% of travellers recommend
Boat Trip "Los Rincones del Guadalquivir"
$30
per adult
82% of travellers recommend
Ticket for Casa de la Guitarra Flamenco Show
$24
per adult
88% of travellers recommend
Explore a world of travel with Expedia
Explore a world of travel with Expedia
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.