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A narrow cobblestone street lined with colorful buildings, shops, and a prominent white archway in the distance.

Santa Cruz Vacations from $1,259

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The Latest Santa Cruz Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Lobby
    Sep 23 - Sep 29

    Eurostars Palace Hotel + Flight

    Distrito Centro
    5 nights
    5.0 star property
    9.0/10 - Wonderful (1,000 reviews)
    Roundtrip • Boston (BOS) - Seville (SVQ)
    BOS - SVQ • 2 stops SVQ - BOS • 1 stop
    $1,668
    $1,259
    per traveler
    found 1 day ago
    Eurostars Palace Hotel
  • Sundeck
    Oct 7 - Oct 12

    Aguilas5 SevillaSuites + Flight

    Historical Center
    4 nights
    4.0 star property
    10/10 - Exceptional (528 reviews)
    "Service was great. They were very response and addressed our concerns. But the property is more 3 stars than 4. We had two small beds together in one room. My wife’s bed was slipping from the end so 20-30 pct was unusable and mattress should be replaced. Bathroom also had duct tape on the ceiling and the shower is barely 2 feet wide. I couldn’t shower without hitting my hand somewhere. Location is great but I wouldn’t stay here again. Would look for an actual 4 star hotel."
    Reviewed April 5, 2026
    Roundtrip • Boston (BOS) - Seville (SVQ)
    BOS - SVQ • 1 stop SVQ - BOS • 1 stop
    Save 100% on your flight
    $2,297
    $1,409
    per traveler
    found 16 hours ago
    Aguilas5 SevillaSuites
  • Rooftop terrace
    Oct 7 - Oct 13

    Hotel Vincci Molviedro Suites Apartments + Flight

    Historical Center
    5 nights
    4.0 star property
    9.8/10 - Exceptional (121 reviews)
    "All the staff were very friendly and extremely helpful. The property is within walking distance to many of the sights but is situated in a lovely peaceful spot. It was very clean and had great air conditioning and a lovely little pool to cool off in. Seville is beautiful and we will definitely be back at some point and I would definitely stay here again."
    Reviewed July 16, 2026
    Roundtrip • Boston (BOS) - Seville (SVQ)
    BOS - SVQ • 1 stop SVQ - BOS • 1 stop
    $2,184
    $1,543
    per traveler
    found 17 hours ago
    Hotel Vincci Molviedro Suites Apartments
  • Terrace/patio
    Oct 7 - Oct 12

    Eurostars Sevilla Boutique + Flight

    Historical Center
    4 nights
    4.0 star property
    9.0/10 - Wonderful (524 reviews)
    "Very attentive personnel."
    Reviewed June 19, 2026
    Roundtrip • Boston (BOS) - Seville (SVQ)
    BOS - SVQ • 1 stop SVQ - BOS • 1 stop
    $1,769
    $1,279
    per traveler
    found 16 hours ago
    Eurostars Sevilla Boutique
  • Interior
    Oct 7 - Oct 12

    Casa de Triana Luxury Suites by Casa del Poeta + Flight

    Triana
    4 nights
    4.0 star property
    10/10 - Exceptional (416 reviews)
    "Amazing place, great staff, location was the best"
    Reviewed July 9, 2026
    Roundtrip • Boston (BOS) - Seville (SVQ)
    BOS - SVQ • 1 stop SVQ - BOS • 1 stop
    $2,130
    $1,624
    per traveler
    found 16 hours ago
    Casa de Triana Luxury Suites by Casa del Poeta

Discover the most popular places to visit in Santa Cruz

A courtyard with a central water feature, surrounded by columns and potted trees.

Royal Alcázar of Seville

9.6/10 (8,220 reviews)
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.

What to do near Santa Cruz

Skip the line combo tour to Alcazar & Cathedral of Seville

Cathedral & Alcázar of Seville Guided Tour Combo

$34
per adult
90% of travelers recommend
Cathedral & Alcázar of Seville Guided Tour Combo
See all activities near Santa Cruz

Santa Cruz Hotel Deals

Reception

Adriano Hotel Boutique Sevilla

Adriano Hotel Boutique Sevilla
3.0 star property
El Arenal, 0.3 mi from Santa Cruz
9.4 out of 10, Exceptional, (1,547 reviews)
"Clean rooms good staff"
$70 nightly
The price is $77
Jul 22 - Jul 23
Total with taxes and fees
Adriano Hotel Boutique Sevilla
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
See all properties in Santa Cruz
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.