Santa Cruz Vacations from $1,087
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Your Santa Cruz Vacation
Booking a Santa Cruz vacation package is a good way to become acquainted with this unique neighborhood. From its must-visit places to its lesser-known treasures, there's a lot to delve into. Some leading nearby attractions to check out during your trip to Santa Cruz include Seville Cathedral, Alcázar and Plaza de España. Whatever your dream Santa Cruz vacation looks like, you can turn it into reality with Expedia.
The Latest Santa Cruz Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Aguilas5 SevillaSuites
Historical Center
Save 100% on your flight
per person
Oct 9 - Oct 15
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Seville (SVQ)
10/10 Exceptional! (515 reviews)
It was cozy and very close to many restaurants and grocery stores
The staff were extremely helpful
I usually don’t bother with ratings but this place definitely deserves some accolades 👏👏👏
Reviewed on Aug 13, 2025
Hotel Vincci Molviedro Suites Apartments
Historical Center
Save 100% on your flight
per person
Oct 9 - Oct 15
found 14 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Seville (SVQ)
9.8/10 Exceptional! (94 reviews)
Pros: On a beautiful relatively quiet plaza. Staff is excellent. Restaurant on site had great food with excellent service. In a great central location. Nicely furnished apartment suites with terrace.
Cons: There was an odor in building 3- smelled like pipes/sewer. We were moved to building 2; the hotel upgraded us to a larger apartment- No odor there. But you can smell at times it throughout the old city.
Overall: Very nice stay. Would recommend.
Reviewed on May 31, 2025
Hotel Boutique Corral del Rey by ALUZ Collection
Historical Center
Save 100% on your flight
per person
Nov 4 - Nov 10
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Seville (SVQ)
9.6/10 Exceptional! (77 reviews)
A delight in all respects. Located in the charming neighborhood of La Alfalfa, the hotel is an easy walk from the Cathedral, Las Setas, ElTorre de Oro, and more. The hotel consists of two buildings and several rooms. Our room was of a decent size and very clean. There was plenty of closet space and a cleverly designed kitchen station hidden behind closet doors. Include the breakfast in your package. Served in the main building, it is a high quality "continental" consisting of fresh fruit, OJ, a basket of croissants/pastries, granola, yogurt and coffee. Most impressive about this establishment is the service. My wife and I were greeted warmly by every staff member we encountered, our breakfast preferences were recalled and every question was cheerfully addressed. This hotel was the anchor of a terrific week in Seville and we hope to revisit again soon.
Reviewed on May 13, 2025
Hotel Las Casas de El Arenal by Casas y Palacios
Historical Center
Save 100% on your flight
per person
Oct 9 - Oct 15
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Seville (SVQ)
9.4/10 Exceptional! (950 reviews)
The air conditioner was amazing for a HOT summer in Sevilla. The area was walkable and the staff was great- we were greeted with drinks and they took care of our taxi requests during our stay. The only drawback was getting a hold of an iron. The room was nice and we had daily service but it was a shame we didn’t have an iron in our room.
Reviewed on Jul 6, 2025
Where to stay in Santa Cruz
Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Historical Center
7 out of top 10 points of interest in this area
Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.
Santa Cruz Hotel Deals
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
San Fernando 2, Seville, Seville
Fully refundableReserve now, pay when you stay
$363 nightly
The price is $399 total per night from Aug 20 to Aug 21
$399 total
Aug 20 - Aug 21
Total includes taxes and fees
9.4/10 Exceptional! (998 reviews)
"Beautiful property, great food, comfortable bed"
Reviewed on Aug 11, 2025
Hotel Rey Alfonso X
Calle Ximenez De Enciso, 35, Seville, Seville
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $146 total per night from Aug 22 to Aug 23
$146 total
Aug 22 - Aug 23
Total includes taxes and fees
9.4/10 Exceptional! (1,040 reviews)
"Can’t fault this hotel, everything was so easy, we checked in early as they said our room was ready which was nice, staff all so lovely. Pool wasn’t too busy each day when we went always got a bed. Would defo come back"
Reviewed on Aug 14, 2025
Las Casas de la Juderia
Calle Santa Maria La Blanca 5, Seville, Seville
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $119 total per night from Aug 20 to Aug 21
$119 total
Aug 20 - Aug 21
Total includes taxes and fees
9.2/10 Wonderful! (1,002 reviews)
"Stunning hotel with super friendly and helpful staff"
Reviewed on Aug 11, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Santa Cruz
Royal Alcázar of Seville
5/5(735 reviews)
Discover a millennium’s worth of royal treasures in this architectural masterpiece in the heart of Seville.
Giralda Tower
4.5/5(496 reviews)
Once among the tallest religious monuments in the world, this former minaret is now the eye-catching bell tower to Seville Cathedral.
San Telmo Palace
Tour the striking interior and exterior of a palatial building that serves as the headquarters of the president of the autonomous region of Andalusia.
Things to do
Skip the Line Seville Alcázar, Cathedral & Giralda Guided Tour
$63
per adult
100% of travellers recommend
Seville: Puro Flamenco Show with Optional Museum Ticket
$29
per adult
98% of travellers recommend
Cathedral & Alcázar of Seville Guided Tour Combo
$38
per adult
92% of travellers recommend
Explore a world of travel with Expedia
Explore a world of travel with Expedia
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.